Which vaccine is contraindicated in patients with a history of Guillain-Barré Syndrome?

The influenza vaccine is contraindicated in patients with a history of Guillain-Barré Syndrome (GBS) because of an association noted between the vaccine and the onset of GBS in a small number of cases. Guillain-Barré Syndrome is a rare neurological disorder that causes weakness and sometimes paralysis. While the risk is low, the specific concern arises from historical data, particularly from the 1976 swine flu vaccination program, where an increase in GBS cases was observed among vaccinated individuals.

In medical practice, it's crucial to weigh the benefits of vaccination against the risks for individuals with a history of GBS. Influenza vaccines are still highly recommended for the general population due to their effectiveness in preventing influenza-related complications, but those with a prior diagnosis of GBS should consult their healthcare provider to determine the best course of action for vaccination.

In contrast, the measles vaccine, tetanus vaccine, and meningococcal vaccine do not carry the same level of concern regarding GBS and are generally considered safe for administration in patients with a history of this syndrome.